What to expect
Inflammation in the body is often linked to stress or physical activity, but not always. C1- inhibitor deficiency can also contribute to inflammation. That helps explain why some HAE attacks seem to occur spontaneously, with no apparent trigger.
HAE attacks are typically prevented or treated by replacing the missing C1-inhibitor protein or by other therapies that block the activity of plasma kallikrein or bradykinin. All the currently approved HAE therapies are delivered by injection.