Healthcare Utilization and Costs Among Hereditary Angioedema Patients Receiving Long-Term Prophylaxis: Results of a Claims Database Analysis

Barriers to Timely On-Demand Treatment of Hereditary Angioedema Attacks in Italian Patients

Efficacy and Safety of Sebetralstat for On-demand Treatment of Hereditary Angioedema in Pooled Analysis of Placebo-controlled Clinical Trials

Barriers to Timely On-Demand Treatment of Hereditary Angioedema Attacks in Italian Patients

Burden of Injectable On-Demand Treatment for Hereditary Angioedema Attacks in Adolescents

Delays in the On-Demand Treatment of Hereditary Angioedema Attacks and Associated Barriers Reported in Different Healthcare Systems

Effectiveness of Sebetralstat for the On-demand Treatment of Laryngeal Hereditary Angioedema Attacks: Interim Analysis from KONFIDENT-S

On-demand Treatment Of Hereditary Angioedema Attacks With Sebetralstat In Adolescents: Pooled Analysis From KONFIDENT And KONFIDENT-S

Study to Adjudicate Hereditary Angioedema with Normal C1INH Diagnoses in the PIONEER-HAE Database

Impact of Long-Term Prophylaxis Adherence in Hereditary Angioedema Patients: Results of a Claims Database Analysis

Safety and Effectiveness of Sebetralstat in Patients with Hereditary Angioedema Receiving Long-term Prophylaxis: Interim Analysis from the KONFIDENT-S Open-label Study

Sebetralstat for Treatment of Hereditary Angioedema Attacks in Patients Receiving Berotralstat: Interim Analysis from the KONFIDENT-S Open-label Study

Efficacy and Safety of Sebetralstat for On-demand Treatment of Hereditary Angioedema in Pooled Analysis of Placebo-controlled Clinical Trials

Patrick Yong, Jonathan Bernstein, Danny Cohn, Henriette Farkas, William Lumry, Marc Riedl, Andrea Zanichelli, James Hao, Michael Smith, Christopher Yea, Paul Audhya, Emel Aygoren-Pursun, Sinisa Savic, Sorena Kiani-Alikhan
Presented at British Society for Immunology Clinical Immunology Professional Network (BSI-CIPN) Conference; December 9-10, 2024; Birmingham, United Kingdom

Impact of Delayed Treatment of Hereditary Angioedema Attacks on Quality of Life and Ability to Work

Impact of Hereditary Angioedema Attacks on Quality of Life and Ability to Work Among UK Patients Receiving Long-term Prophylaxis or On-demand Only

Correlation of Time to Treatment with Attack Duration in the Sebetralstat KONFIDENT Phase 3 Trial

Indirect Treatment Comparison of Oral Sebetralstat and Intravenous rhC1-INH as On-demand Treatments for Hereditary Angioedema

On-demand Treatment of Laryngeal Hereditary Angioedema Attacks with Sebetralstat: Pooled Analysis from KONFIDENT and KONFIDENT-S

Patient-Reported Anxiety Impacts Utilization of Injectable On-demand Treatment of Hereditary Angioedema Attacks

Substantial Reduction of Hereditary Angioedema Attack Symptom Burden in the Sebetralstat Phase 3 KONFIDENT Trial

Real World Barriers to On-Demand Treatment for Attacks in Hereditary Angioedema: A Patient Survey

Anxiety Associated with Parenteral On-Demand Treatment for Hereditary Angioedema Attacks

Global Frequency and Diagnosis of Hereditary Angioedema with Normal C1INH: A Real World ACARE Survey

Impact of Oral Sebetralstat on Hereditary Angioedema Attack-associated Anxiety: Analysis From the Phase 3 KONFIDENT Trial

KONFIDENT Trial of Oral Sebetralstat for Treatment of Hereditary Angioedema Attacks: Analysis of the European and US Patient Populations

Delayed On-demand Treatment of Hereditary Angioedema Attacks: Italian Patient Perceptions and Associated Barriers

A Specific, Sensitivity Assay Measuring Patient Sample Plasma Kallikrein Activity

Delayed On-demand Treatment of Hereditary Angioedema Attacks and Associated Barriers Reported by Italian Patients

KONFIDENT-S Interim Analysis: Sebetralstat for Hereditary Angioedema Attacks Including Laryngeal

Pooled Sebetralstat Placebo-controlled Efficacy for On-demand Treatment of Hereditary Angioedema

Pooled Sebetralstat Placebo-controlled Safety for On-demand Treatment of Hereditary Angioedema

Anxiety Associated with On-demand Treatment of Hereditary Angioedema (HAE) Attacks

Attack Characteristics in Patients with Hereditary Angioedema Receiving Non-Androgen Long-term Prophylaxis

Delayed On-demand Treatment of Hereditary Angioedema Attacks: Patient Perceptions and Associated Barriers

Hereditary Angioedema (HAE) Patients Answer: Why Do Attacks Go Untreated?

Patient-Reported Benefits of Early On-Demand Treatment of HAE Attacks

Sebetralstat as Oral On-demand Treatment for Hereditary Angioedema: Interim Analysis of the Open-label KONFIDENT-S Trial

Treatment of HAE Attacks with Anticipated Future Oral On-Demand Therapies as Reported by Patients

Unmet Needs Associated with Non-androgen Injectable Long-term Prophylaxis (LTP) Therapies for HAE

Burden of Untreated Hereditary Angioedema Attacks and its Impact on Social, Mental, and Physical Health

Healthcare Costs Among Commercially-Insured Patients with Hereditary Angioedema Managed with Long-Term Prophylaxis: A Retrospective US Claims Database Analysis

Real-World Impact of Treated Hereditary Angioedema Attacks on Patients’ Employment and Work Productivity

Real-World Impact of Treated Hereditary Angioedema Attacks on Patients’ Quality of Life

Sebetralstat for On-demand Treatment of Hereditary Angioedema Attacks: US Subgroup Analysis from the Double-blind, Placebo-controlled Phase 3 KONFIDENT Trial

Trends in Volume of On-demand Hereditary Angioedema Treatments in the US: A Retrospective Analysis of a Large Multi-payer Claims Database

Factor XIIa Inhibition Protects Against VEGF-Induced Neuroretinal Dysfunction in Mice

Healthcare Costs Among Commercially-Insured Patients with Hereditary Angioedema Managed with Long-Term Prophylaxis: A Retrospective US Claims Database Analysis

Relationship Between Time to On-demand Treatment and Quality of Life During Hereditary Angioedema Attacks

Anxiety Associated with On-demand Treatment of Hereditary Angioedema (HAE) Attacks

Anxiety Associated with Refilling On-demand Therapy for HAE Attacks Contributes to Treatment Delay and Non-Treatment

Characteristics of Hereditary Angioedema Attacks Among Long-term Prophylaxis Users

Characterizing the Negative Impact of Delayed On-Demand Treatment of HAE Attacks

Characterizing the Perspectives of Patients with HAE on Prophylactic Treatment

Delayed Treatment of Hereditary Angioedema Attacks: Patient Perceptions and Associated Barriers

The Impact of On-demand Treatment on Quality of Life of People with HAE

Burden of Hereditary Angioedema Attacks in Adolescents

Quality of Life Among Prophylaxis Plus On-Demand and On-Demand Only Therapy Users in HAE

Anxiety Associated with On-demand Treatment of Hereditary Angioedema (HAE) Attacks May Result in Sub-optimal Attack Management

Understanding Why Hereditary Angioedema Patients Often Do Not Carry Their On-Demand Treatment with Them

KONFIDENT Phase 3 Trial Global Expansion: Sebetralstat Pharmacokinetics and Pharmacodynamics in Japanese and Chinese Adults

Reporting of Administration Site Reactions with Parenteral Drugs for the On-demand Treatment of Hereditary Andioedema Attacks – Analysis of the FAERS Database 2009 – 2022

The Discovery of Sebetralstat, an Oral, Small Molecule Plasma Kalkrein Inhibitor to Treat Attacks of Hereditary Angioedema

In Their Own Words – Patients Descriptions of the Earliest Recognition of Hereditary Angioedema Attack Onset

Preferences of People with Hereditary Angioedema for On-demand Treatment: A US Based Qualitative Study

Recognizing the Importance of Early On-demand Treatment in the Hereditary Angioedema (HAE) Attack Journey

Patients Delay Treating Hereditary Angioedema (HAE) Attacks with Currently Available, Injectable, On-demand Therapies

Remaining Burden of Hereditary Angioedema (HAE) Attacks Despite Modern Long-term Prophylaxis

Results From a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial Evaluating Sebetralstat Pharmacokinetics, Pharmacodynamics, and Safety/Tolerability in Healthy Japanese, Chinese, and White Adults

Short-term Prophylaxis with Sebetralstat, an Investigational On-demand Treatment for Hereditary Angioedema, in KONFIDENT-S

Understanding the Complex Decision-Making Associated with On-Demand Treatment of Hereditary Angioedema (HAE) Attacks

Sebetralstat Effectiveness in the Treatment of Hereditary Angioedema Attacks Rated Mild or Moderate at Baseline in the Phase 2 Trial

HAE Patients’ Decision to Carry On-demand Treatment When Away from Home

Rationale for the Short-term Prophylaxis Regimen with Sebetralstat in KONFIDENT-S

Route of Administration Preferences of People Living with Hereditary Angioedema for On-demand Treatment: A US Based Qualitative Study

Anxiety Associated With Parenteral On-demand Treatment For Hereditary Angioedema (HAE)

Comparative Bioavailability of Sebetralstat Following Administration of Orally Disintegrating Tablets and Film-Coated Tablets in Healthy Volunteers

Treatment with Sebetralstat Reduces the Cumulative Symptom Severity of Hereditary Angioedema Attacks in a Phase 2 Trial

Efficacy of the Oral Plasma Kallikrein Inhibitor Sebetralstat (KVD900) by Attack Location in a Phase 2 Clinical Trial in Patients with Hereditary Angioedema

Pharmacokinetic, Pharmacodynamic, and Safety Profile in Healthy Japanese and White Adults: Results from Phase 1, Randomized, Double-blind, Placebo-controlled Trial

Targeted Literature Review to Assess the Studies Supporting Short-term Prophylactic Treatment Options for the Preprocedural Prevention of Attacks in Patients with Hereditary Angioedema

Patient Perspectives on an Optimal Outcome Measure to Assess Efficacy in the Acute Treatment of Hereditary Angioedema Attacks

Population Pharmacokinetic Analysis of Sebetralstat (KVD900) in Healthy Volunteers and Patients with Hereditary Angioedema Predicts Similar Exposure in Adolescent Patients

Agreement Between Improvements in Patient Global Assessment of Change and Other Measures of Improvement and Attack Resolution Observed in a Phase 2 Trial with Sebetralstat (KVD900) in Patients with Hereditary Angioedema

Agreement of Patient Global Assessment of Change With Attack Resolution or Use of Rescue Medication in Patients with Hereditary Angioedema