Treatment with Sebetralstat Reduces the Cumulative Symptom Severity of Hereditary Angioedema Attacks in a Phase 2 Trial

Bernstein JA, Riedl MA, Lumry WR, Audhya PK, Smith MD, Yea CM

AAAAI 2023

A Comparative Bioavailability of Sebetralstat Following Administration of Orally Disintegrating Tablets and Film-Coated Tablets in Healthy Volunteers

Smith MD, Iverson M, Hansen E, Audhya PK, Yea CM

AAAAI 2023

Patient Perspectives On Early Use Of On-demand Treatment For Hereditary Angioedema (HAE) Attacks to Reduce Severity and Duration

Radojicic C, Manning M, Guilarte M, Heckmann M, van Kooten S, Danese S, Goga L

AAAAI 2023

Factor XII contributes to VEGF-induced retinal edema and neuroretinal responses in mice

Clermont AC, Murugesan N, Ustunkaya T, Aiello LP, Feener EP

ARVO 2023

Reporting of Adverse Drug Reactions with Parenteral Drugs for the On-Demand Treatment of Hereditary Angioedema Attacks – Analysis of the FAERS Database 2009 to 2022

Tachdjian R, Savi S, Fridman M, Frade J, Audhya PK, Fasehun M

AAAAI 2023

Targeted Literature Review to Assess the Studies Supporting Short-term Prophylactic Treatment Options for the Preprocedural Prevention of Attacks in Patients With Hereditary Angioedema

Riedl MA, Bernstein JA, Lumry WR, Audhya PK, Smith MD, Yea CM

WSAAI 2023

Pharmacokinetic, Pharmacodynamic, and Safety Profile of Sebetralstat in Healthy Japanese and White Adults: Results From a Phase 1, Randomized, Double-Blind, Placebo-Controlled Trial

Iverson M, Jhee S, Hansen E, Duckworth EJ , Hampton SL, Yoon E

WSAAI 2023

Efficacy of the Oral Plasma Kallikrein Inhibitor Sebetralstat (KVD900) by Attack Location in a Phase 2 Clinical Trial in Patients With Hereditary Angioedema

Aygören-Pürsün E, Zanichelli A, Cohn DM, Audhya PK, Williams P, Yea CM, Smith MD
WSAAI 2023