Factor XII contributes to VEGF-induced retinal edema and neuroretinal responses in miceClermont AC, Murugesan N, Ustunkaya T, Aiello LP, Feener EP
ARVO 2023
Reporting of Adverse Drug Reactions with Parenteral Drugs for the On-Demand Treatment of Hereditary Angioedema Attacks – Analysis of the FAERS Database 2009 to 2022Tachdjian R, Savi S, Fridman M, Frade J, Audhya PK, Fasehun M
AAAAI 2023
Targeted Literature Review to Assess the Studies Supporting Short-term Prophylactic Treatment Options for the Preprocedural Prevention of Attacks in Patients With Hereditary AngioedemaRiedl MA, Bernstein JA, Lumry WR, Audhya PK, Smith MD, Yea CM
WSAAI 2023
Pharmacokinetic, Pharmacodynamic, and Safety Profile of Sebetralstat in Healthy Japanese and White Adults: Results From a Phase 1, Randomized, Double-Blind, Placebo-Controlled TrialIverson M, Jhee S, Hansen E, Duckworth EJ , Hampton SL, Yoon E
WSAAI 2023
Efficacy of the Oral Plasma Kallikrein Inhibitor Sebetralstat (KVD900) by Attack Location in a Phase 2 Clinical Trial in Patients With Hereditary AngioedemaAygören-Pürsün E, Zanichelli A, Cohn DM, Audhya PK, Williams P, Yea CM, Smith MD
WSAAI 2023
Impact of Hereditary Angioedema (HAE) Attacks on Quality of Life and Activities of Daily LivingBusse PJ, Caballero T, van Kooten S, Danese S, Goga L
ACAAI 2022
Real-World Treatment Burden Associated with Parenteral On-Demand Therapies for Hereditary AngioedemaTachdjian R, Savic S, Fridman M, Frade J, Audhya PK, Fasehun M
ACAAI 2022
Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On Demand Treatment for Hereditary AngiodemaDavie R, Edwards H, Evans D, Hodgson S, Stocks M, Smith A, Rushbrooke L, Pethen S, Roe M, Clark D, McEwan P, Hampton S
PMID: 36251573
Absorption, metabolism, and excretion of [14C]-sebetralstat (KVD900 following a single oral does in healthy male participantsMutch P, Bashir M, Jung B, Yi P, Iverson M
PMID: 36200371
The Global and Regional Impact of Hereditary Angioedema (HAE) Attacks on Mental Health, Activities of Daily Living and Quality of LifeBusse PJ, Caballero T, van Kooten S, Danese S, Goga L
2022 HAEi Global Leadership Workshop
